Merck results beat expectations on strong Keytruda, Gardasil and Covid drug growth


Merck headquarters in Rahway, New Jersey, on Tuesday, April 18, 2023.

Christopher Occhicone | Bloomberg | Getty Images

Merck on Thursday reported third-quarter income and adjusted earnings that topped expectations on strong gross sales of its blockbuster most cancers drug Keytruda, HPV vaccine Gardasil and surprisingly, its Covid drug Lagevrio. 

The pharmaceutical large additionally elevated its full-year gross sales forecast to $59.7 billion to $60.2 billion, barely greater than the $58.6 billion to $59.6 billion steering offered in August. 

Merck lowered its adjusted revenue steering to $1.33 to $1.38 per share, from a earlier forecast of $2.95 to $3.05 a share. But that up to date outlook displays an upfront cost of $5.5 billion, or $1.70 per share, associated to the corporate’s current drug collaboration settlement with Daiichi Sankyo. That steering additionally contains beforehand introduced one-time costs associated to the corporate’s acquisitions of Prometheus Biosciences and Imago Prometheus BioSciences, together with one other upfront fee associated to a collaboration cope with Kelun-Biotech. 

Here’s what Merck reported for the third quarter in contrast with what Wall Street was anticipating, primarily based on a survey of analysts by LSEG, previously often known as Refinitiv:

  • Earnings per share: $2.13 adjusted vs. $1.95 anticipated
  • Revenue: $15.96 billion vs. $15.32 billion anticipated

Shares of Merck are down practically 7% this 12 months. It has a market worth of roughly $263 billion, making it the third-largest pharmaceutical firm primarily based within the U.S.

Merck raked in $15.96 billion in income for the quarter, up 7% from the identical interval a 12 months in the past. 

The firm posted web revenue of $4.75 billion, or $1.86 per share. That compares with $3.25 billion, or $1.28 per share, for a similar interval a 12 months in the past. 

Excluding sure objects, Merck’s adjusted earnings per share have been $2.13 for the interval. 

Merck’s pharmaceutical enterprise, which develops a variety of medication for various illness areas, posted $14.26 billion in income through the quarter. That’s up 10% from the identical interval a 12 months in the past. 

Excluding Lagevrio, gross sales grew 9%. The Covid antiviral therapy raked in $640 million in gross sales for the quarter, up 47% from the third quarter of 2022. Merck mentioned that growth was on account of greater demand in Japan, partially offset by decrease demand in Australia and the nonrecurrence of gross sales within the U.Ok.

Analysts had been anticipating the drug to rake in solely $140.8 million in gross sales, based on FactSet estimates. Lagevrio’s gross sales are shocking since gross sales of Covid merchandise from firms like Pfizer and Moderna have plummeted this 12 months because the world emerges from the pandemic and depends much less on vaccines and therapies for cover. 

Merck’s in style antibody therapy Keytruda, which is used to deal with a number of kinds of most cancers, booked $6.34 billion in income, up 17% from the year-earlier quarter. Analysts had been anticipating $6.20 billion in Keytruda gross sales, FactSet estimates mentioned.

The firm has been below stress to cut back its dependence on Keytruda, which is slated to lose patent safety in 2028. But Merck is attempting to defend its patent edge over Keytruda by growing new formulations of the drug, akin to a model that may be injected below the pores and skin.

Merck’s pharmaceutical enterprise additionally noticed a leap in gross sales of Gardasil, a vaccine that forestalls most cancers from HPV, the most typical sexually transmitted an infection within the U.S.

Gardasil generated $2.59 billion in gross sales, which is up 13% from the third quarter of 2022. Analysts had been anticipating gross sales of $2.64 billion, based on FactSet estimates.

The firm’s animal well being division, which develops vaccines and medicines for canine, cats and cattle, posted $1.40 billion in gross sales, up 2% from the identical interval a 12 months in the past.

Merck will maintain a conference call at 9 a.m. ET on Thursday.



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