Eli Lilly says supply of blockbuster diabetes drug Mounjaro has improved in U.S.
Eli Lilly says supply of blockbuster diabetes drug Mounjaro has improved in U.S.

A pharmacist shows containers of Ozempic, a semaglutide injection drug used for treating sort 2 diabetes made by Novo Nordisk, at Rock Canyon Pharmacy in Provo, Utah, March 29, 2023.

George Frey | Reuters

Eli Lilly on Thursday mentioned supply of its blockbuster diabetes drug Mounjaro has improved in the U.S. after months of widespread shortages. 

However, the pharmaceutical large famous that it’s nonetheless working to extend manufacturing capability for the remedy and different medicine amid elevated demand.

The remarks recommend that Eli Lilly’s preliminary efforts to increase manufacturing capability for Mounjaro are beginning to repay. Demand for the remedy is hovering, largely as a consequence of its off-label potential to trigger vital weight reduction. U.S. regulators may probably approve the drug for weight reduction this 12 months, which may push up demand much more.

During an earnings name Thursday, Eli Lilly executives mentioned the corporate skilled tight supply for Mounjaro all through most of the third quarter. Mounjaro raked in $1.4 billion in gross sales for the quarter, serving to the corporate beat expectations on each the highest and backside traces. 

But U.S. product shipments of Mounjaro have lately elevated, and stock ranges at U.S. drug wholesalers have improved, in keeping with Eli Lilly CFO Anat Ashkenazi. 

She famous that each one doses of Mounjaro at the moment are listed as accessible on the Food and Drug Administration’s scarcity database. Meanwhile, Mounjaro supply stays tight internationally, Ashkenazi added. 

Eli Lilly is on monitor to attain its purpose of doubling manufacturing capability for medicine like Mounjaro and its different diabetes remedy Trulicity, Ashkenazi mentioned. Both medicine work by mimicking hormones produced in the intestine known as incretins to suppress an individual’s urge for food and regulate blood sugar. 

Ashkenazi pointed to the corporate’s new facility in North Carolina, which is now “on-line” to offer further drug meeting capability. Eli Lilly has additionally invested greater than $3 billion to build two new manufacturing websites in its residence state of Indiana.

But Eli Lilly CEO David Ricks mentioned through the earnings name that the corporate remains to be “aggressively planning” additional manufacturing build-up for Mounjaro and different medicine.

He famous that the corporate has been inking third-party manufacturing agreements with a “various portfolio” of contractors, with Eli Lilly “shopping for up as a lot capability as accessible” in their techniques. 

“This is absolutely all-hands-on-deck,” Ricks mentioned. “It’s an issue we work on day by day. So we’re by no means pleased with the capability.”

Eli Lilly’s foremost rival in the burden loss drug area, Novo Nordisk, remains to be navigating its personal supply constraints of diabetes drug Ozempic and weight problems remedy Wegovy.

Ozempic and Wegovy sparked the burden loss business gold rush final 12 months, pushing Eli Lilly and different corporations like Pfizer to ramp up their investments in the area. 

Initial research have advised that Eli Lilly’s Mounjaro could also be much more efficient at decreasing weight than Wegovy and Ozempic.

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